Feb 17, 2020 · If using concurrent simvastatin in patients with moderate to severe renal impairment (CrCl <60 mL/minute/1
Ezetimibe/Simvastatin Sandoz is available for oral use as tablets containing 10 mg of ezetimibe, and 10 mg of simvastatin (Ezetimibe/Simvastatin Sandoz 10/10), 20 mg of simvastatin (Ezetimibe/Simvastatin Sandoz 10/20), 40 mg of simvastatin (Ezetimibe/Simvastatin Sandoz 10/40), or 80 mg of simvastatin Common simvastatin side effects may include: headache; constipation, nausea, stomach pain; or
Generic name: ezetimibe and simvastatin [ ez-ET-i-mibe-and-SIM-va-stat-in ] Brand name: Vytorin Dosage form: oral tablet (10 mg-10 mg; 10 mg-20 mg; 10 mg-40 mg; 10 mg-80 mg) Drug class: Antihyperlipidemic combinations Medically reviewed by Drugs
What Are Side Effects Associated with Using Simvastatin-Ezetimibe?
Vytorin reduces total cholesterol and low density lipoprotein
It is a combination of ezetimibe (known as Zetia in the United States) and the statin drug
stomach fullness
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This does not necessarily mean no interactions exist
May initiate at 10/40-mg orally once a day if a larger reduction in LDL-C is needed (e
Ezetimibe is a type of medicine called a cholesterol absorption inhibitor
Medication Uses | How To Use | Side Effects | Precautions | Drug Interactions | Overdose | Notes | Missed Dose | Storage
(Controlled trial of ezetimibe/simvastatin versus atorvastatin alone in 1128 patients with metabolic syndrome and hypercholesterolemia Do not take colestipol, cholestyramine, or colesevelam within 4 hours before or 2 hours after ezetimibe and simvastatin
Simvastatin is used together with a proper diet to treat high cholesterol and triglyceride (fat) levels in the blood
In patients requiring >55% reduction in LDL-cholesterol: Initially, 10 mg/40 mg
itching, unusual tiredness; or
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Rosuvastatin is an HMG-CoA reductase inhibitor or statin and ezetimibe is a cholesterol absorption inhibitor
Drug therapy is indicated as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other nonpharmacologic measures alone has been inadequate
Ezetimibe-Simvastatin is a generic prescription cholesterol-reducing drug that is a generic alternative to brand-name Vytorin
Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities
Simvastatin reduces cholesterol by inhibiting the conversion of HMG-CoA to mevalonate, an early step in the biosynthetic pathway for cholesterol
No Interactions Found
Use with caution in patients with severe renal impairment (CrCl ≤30 mL/min/1
1 * Administer NEXLIZET either at least 2 hours before, or at least 4 hours after, bile acid sequestrants
1 Mechanism of Action - Ezetimibe reduces blood cholesterol by inhibiting the absorption of cholesterol by the small intestine